That sounds like a lot to manage. In 10 years, you'd own stock in over 100 companies. Unless you're a financial pro with a deep bench of analyst support, that sounds overwhelming to me.
That's unless, of course, you plan on just buying and holding, never trimming a holding or rebalancing. In that scenario, you'd have to be content to let most stocks (potentially) go to zero in the hope that perhaps one a year goes to the moon eventually.